uses an all natural proprietary blend herbal formula.
Ingredients in StoneCLR include Phyllanthus Nirui
(Chanca Piedra), Parsley (Leaves), Marshmellow (Root),
Turmeric (Root) Ext. 95%, Ginger (Root), Gravel (Root),
Lemon Balm (Leaf), Dandelion (Root), Licorice (Root).
Nirui is a plant that grows in the Amazon Rainforest
and other tropical areas of the world. Also known
as chanca or quebra pedra, the name translates to
“stone breaker” or “shatter stone,”
which comes from its ability to eliminate kidney
stones & gallstones from the body. The plant
contains stone-like berries underneath its leaves.
This makes it a good example of morphism, where
a plant’s shape signals its effective bodily
The first notable area of study has validated chanca piedra's longstanding traditional use for kidney stones. In 1990, the Paulista School of Medicine in São Paulo, Brazil, conducted studies with humans with kidney stones. They were given a simple tea of chanca piedra for 1-3 months and it was reported that the tea promoted the elimination of stones. They also reported a significant increase in urine output as well as sodium and creatine excretion. Subsequently the medical school educated new doctors about the ability to treat kidney stones with this natural remedy and now it is found in many pharmacies throughout Brazil.
While indigenous inhabitants of the Amazon have been using Phyllanthus Nirui for generations for kidneystones, scientific researchers have been validating the herb’s effectiveness in eliminating kidney stones since the 1980’s. Phyllanthus can help relax urinary muscles, thus, making it easier to expel kidney stones.
The conventional approach to removal of kidney stones usually involves shattering the stone using ESWL (Extracorporeal Shockwave Lithotripsy) but this often leaves residual fragments which often require the treatment to be repeated, not to mention the high costs involved. The new research, published in the medical journal 'European Urology Supplements' earlier this year, assessed the benefit of taking an extract of Phyllanthus carolinianus following ESWL treatment. After six months the stone free rate in those treated with just ESWL was 80% - but for the patients taking Quebra Pedra during their recovery, the stone free rate was 97%. Concerning lower caliceal stones the stone free rate of those using the herb was 94.1% versus 64.28% among those who just had ESWL.
Phyllanthus Nirui traditional uses for kidney stones have been validated by clinical research. In a 1999 clinical study (Campos, A.H., et. al.) a Phyllanthus Nirui extract extract exhibited a potent and effective non-concentration-dependent inhibitory effect on the calcium oxalate crystal formation (the building blocks of most kidney stones). This response was present even at very high (pathologic) concentrations. This may explain why it has long been used in traditional medicine as a preventative to kidney stone formation. The antispasmodic activity of alkaloids in Phyllanthus Nirui were documented by Brazilian researchers in the mid 1980's which explained the popular use of the plant for existing kidney and bladder stones. The alkaloid extract demonstrated smooth muscle relaxation specific to the urinary and Biliary tract, which the researchers surmised, facilitates the expulsion of kidney or bladder calculi. Dr. Wolfram Wiemann of Nuremburg, Germany review over 100 case studies and found Phyllanthus Nirui to be 94% successful in eliminating stones. (Maxwell, N. 1990)
References on Kidney Stones.
Murugaiyah V, et al. "Antihyperuricemic lignans from the leaves of Phyllanthus niruri ." Planta Med . 2006 Nov; 72(14): 1262-7.
Micali, S., et al. "Can Phyllanthus niruri affect the efficacy of extracorporeal shock wave lithotripsy for renal stones? A randomized, prospective, long-term study." J. Urol. 2006 Sep; 176(3): 1020-2.
Barros, M. E., et al. "Effect of extract of Phyllanthus niruri on crystal deposition in experimental urolithiasis." Urol. Res. 2006 Aug 1;
Nishiura, J. L., et al. “ Phyllanthus niruri normalizes elevated urinary calcium levels in calcium stone forming (CSF) patients.” Urol. Res . 2004 Oct; 32(5): 362-6.
Barros, M. E., et al. “Effects of an aqueous extract from Phyllanthus niruri on calcium oxalate crystallization in vitro.” Urol. Res . 2003; 30(6): 374-9.
Freitas, A. M., et al. “The effect of Phyllanthus niruri on urinary inhibitors of calcium oxalate crystallization and other factors associated with renal stone formation.” B. J. U. Int. 2002; 89(9): 829–34.
Campos, A. H., et al. “ Phyllanthus niruri inhibits calcium oxalate endocytosis by renal tubular cells: its role in urolithiasis.” Nephron. 1999; 81(4): 393–97.